This article is a curated recap of a recent conversation between Dr. Peter McCullough and Dr. Michael Gaeta on the McCullough Report, focused on the McCullough Protocol for base spike detoxification. As a physician, I'm presenting the key clinical insights from this discussion — not as endorsement, but as intelligence.
Why a Financial Advisory Firm Is Covering This
We get asked this. Our answer is simple: what good is a compounding portfolio if you're not around to enjoy it? CI Mavericks operates at the intersection of wealth and health because the two are inseparable for the people we serve. Our members are founders, investors, and operators who need their bodies to last as long as their businesses.
Dr. Peter McCullough is a cardiologist, internist, and epidemiologist. He is the co-author of The Courage to Face COVID-19, founder of the McCullough Foundation, and chief scientific officer and co-founder of The Wellness Company. He has authored or co-authored over 700 peer-reviewed publications.
The Core Problem: A Protein the Body Can't Break Down
The SARS-CoV-2 spike protein — the spicule structure on the surface of the virus — is approximately 1,200 amino acids in length with roughly a dozen glycosylated side chains. According to Dr. McCullough, this protein was engineered to dock with human ACE2 receptors, which are present on virtually every cell type in the human body.
The critical distinction: the human body has natural proteases that break down most viral proteins. Influenza, staphylococcal toxin — these get cleared. But the spike protein, he argues, resists normal human enzymatic degradation.
The McCullough Protocol: Base Spike Detoxification
Developed in 2022, published in 2023, and now approaching four years of clinical use across thousands of patients, the protocol centers on three natural compounds:
Nattokinase — a proteolytic, thrombolytic enzyme derived from the fermentation of soy or chickpeas. It has been demonstrated to dissolve spike protein in preclinical studies. Protocol dose: 8,000 fibrinolytic units (two capsules twice daily).
Bromelain — a family of proteolytic enzymes derived from pineapple stems. It functions as a natural anticoagulant and has shown the ability to physically dissolve spike protein in preclinical models. Protocol dose: 500 mg (two capsules twice daily).
Curcumin — derived from turmeric, a natural anti-inflammatory that has demonstrated anti-SARS-CoV-2 properties in human randomized trials. Should be taken in liposomal, micronized, or biopiperine-enhanced form. Protocol dose: 1,000 mg (two capsules twice daily).
The Expanded Protocol: Additional Interventions
N-Acetylcysteine (NAC) — added to the base protocol for its detoxification properties.
Sweating — McCullough considers this a critical, non-supplement intervention. Since spike protein and synthetic mRNA have been identified in skin and sweat glands via biopsy, sweating represents a measurable excretion pathway. Infrared saunas, outdoor exercise in heat, and any activity producing perspiration are actively recommended.
Hyperbaric oxygen therapy — at least 20 sessions at 100% oxygen at two to three atmospheres. Every published study on this intervention has been positive.
Monitoring: How to Measure Your Exposure
McCullough recommends quantitative antibody testing against the spike protein through Lab Corp using the Roche Elecsys system. This can be self-ordered at labcorp.com under "Labs on Demand" for $69 — no physician order required.
Below 1,000 units/mL — very low risk post-exposure. Most people with one or two prior infections and no vaccine fall in this range.
Around 2,000 units/mL — average for patients with long COVID syndrome.
Around 11,000 units/mL — average for patients with vaccine-related syndromes.
Over 25,000 units/mL — Lab Corp's current reporting ceiling, though they can measure up to 100,000 with additional dilutions.
The CI Mavericks Takeaway
I'm presenting this as curated intelligence — not prescription. As a physician, I can evaluate the clinical reasoning here, and I find it substantive enough to warrant our members' attention. The peer-reviewed literature on spike protein persistence is real. The clinical observations across thousands of patients are documented. The protocol compounds have established safety profiles when used appropriately.
Whether you had the infection, the vaccine, or both, the question McCullough raises is worth sitting with: is the spike protein still in your body, and what are you doing about it?
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